Integrative Biology Platform

Director: Dr. John Rioux; Canada Research Chair in Genetics and Genomic Medicine and Associate Professor of Medicine at the Université de Montréal and Montreal Heart Institute.

Co-director: Dr. Ramnik Xavier; Chief of Gastroenterology at the Massachusetts General Hospital of Harvard University, Adjunct Professor of Medicine at Université de Montréal and co-founder of the Center for Computational and Integrative Biology.

Manager: Dr. Guy Charron


Capabilities

Our custom-designed Integrative Biology Platform consists of a state-of-the-art integrated automation platform equipped to handle a multitude of functional screens. Its built-in flexibility allows users to meet the needs of many applications. Software and design features permit the simultaneous operation of two independent screens. At the core of the platform is a robotic arm connecting two Tecan Freedom Evo200 liquid handlers. Each liquid handler is equipped with various pipetting modules, including an 8-channel arm, a 96-channel arm and several plate washers and bulk reagent dispensers. The system is enclosed in custom-built laminar flow hoods. High-content analysis is made possible by the GE In Cell Analyzer 2000, a lamp-based cellular and sub-cellular automated imaging system, and the GE In Cell Analyzer 6000, a laser-based confocal automated imaging module. The Tecan M1000 is a multifunctional plate reader that is designed to handle the latest technologies. High capacity incubators and hotels and an integrated freezer allow routine screens of hundreds of plates in a single run. Combined with remote error handling capabilities and automated sample and data management, the Integrative Biology Platform is ready to meet the most challenging demands.